Answer
Pyruvate produced by the glycolysis act as the precursor for gluconeogenesis (synthesis of glucose from non carbohydrate compounds). In the process of gluconeogenesis, the pyruvate first converts into phosphoenolpyruvate and then this phosphoenolpyruvate undergoes reversal of glycolysis until fructose 1,6 biphosphate is produced. The enzyme fructose 1,6-biphosphatase converts fructose 1,6-biphosphate to fructose 6 phosphate which finally convert into glucose. Hence if there will be deficiency of 1,6-biphosphatase then thye conversion of fructose 1,6-biphosphate will be reduced and the level of fructose 1,6-biphosphate will increase and thus ultimately the level of pyruvate will be increased.
Work Step by Step
Pyruvate produced by the glycolysis act as the precursor for gluconeogenesis (synthesis of glucose from non carbohydrate compounds). In the process of gluconeogenesis, the pyruvate first converts into phosphoenolpyruvate and then this phosphoenolpyruvate undergoes reversal of glycolysis until fructose 1,6 biphosphate is produced. The enzyme fructose 1,6-biphosphatase converts fructose 1,6-biphosphate to fructose 6 phosphate which finally convert into glucose. Hence if there will be deficiency of 1,6-biphosphatase then thye conversion of fructose 1,6-biphosphate will be reduced and the level of fructose 1,6-biphosphate will increase and thus ultimately the level of pyruvate will be increased.
