Answer
Insulin is a hormone secreted by beta islet cells of pancreas that maintains glucose homeostasis. When excess amount of glucose is present in glucose, insulin converts it into glycogen that to be stored in muscle cells When insulin receptor is absent, insulin cannot bind with insulin receptor and cannot activate gluconeogenesis process. Hence after a meal, the food is converted into glucose and that will be stored as glycogen if insulin and insulin receptors perform well In the absence of insulin receptor, the glucose present in the blood remains same and causes high blood sugar concentration Hence the circulating blood sugar concentration will be high. rate of glycogen synthesis in muscle is reduced since insulin receptor is not present.
Work Step by Step
Insulin is a hormone secreted by beta islet cells of pancreas that maintains glucose homeostasis. When excess amount of glucose is present in glucose, insulin converts it into glycogen that to be stored in muscle cells When insulin receptor is absent, insulin cannot bind with insulin receptor and cannot activate gluconeogenesis process. Hence after a meal, the food is converted into glucose and that will be stored as glycogen if insulin and insulin receptors perform well In the absence of insulin receptor, the glucose present in the blood remains same and causes high blood sugar concentration Hence the circulating blood sugar concentration will be high. rate of glycogen synthesis in muscle is reduced since insulin receptor is not present.
