Answer
$(x^2+4)(x+2)(x-2)$
Work Step by Step
Use the formula $a^2-b^2=(a+b)(a-b)$. Then use it again for the second set of parentheses to factor completely.
$x^4-16$
$(x^2+4)(x^2-4)$
$(x^2+4)(x+2)(x-2)$
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