Answer
A ten-fold increase in the rate of teh reaction at 25°C leads to a decrease of approximately 5.7 kJ/mol in the activation free energy.
In case of the staphylococcal nuclease the rate of enhancement of the reaction on the order of 1014 will lead to a decrease of about
14 * 5.7 = 80kJ/mol in the activation free energy. Therefore, staphylococcal nuclease decrease the Delta G++ approximately 80 kJ/mol.
Work Step by Step
A ten-fold increase in the rate of teh reaction at 25°C leads to a decrease of approximately 5.7 kJ/mol in the activation free energy.
In case of the staphylococcal nuclease the rate of enhancement of the reaction on the order of 1014 will lead to a decrease of about
14 * 5.7 = 80kJ/mol in the activation free energy. Therefore, staphylococcal nuclease decrease the Delta G++ approximately 80 kJ/mol.
